BBM for Android and iOS

The announcement of plans for multi-platform BBM was a big surprise for everyone. Since then, however, been a while and we all want information on BlackBerry's plans for launch, in view of the fact that the premiere is fast approaching, let's recap all the news.

When?
According to the official announcement of the application for both iOS and Android will be held this summer. Theoretically, BBM would be available for the last week of September.

Who?
The new edition of the application is designed for smartphones running Android version 4.0 and iOS 6.0 or later. No special editions planned for tablets will therefore be impossible to make it work both iPad and Android tablets.

NOTE: Because the PlayBook operating system Android supports only version 2.3 applications can not be entered by the method BBM to the PlayBook

What price will?
The application will be free.

What do they look together?
Both Android and iOS version are similar in terms of the interface to the operating system edition BlackBerry 10 In fact, almost identical.

What will the first version of BBM?
The first version of BBM for Android and iOS will:

•     Chat File Sharing text and voice messages
•     Share location
•     Change in condition
•     Change profile picture Creating groups up to 30 people
•     Join a group
•     Invite and be invited via QR code

You are the first functions of the first version of BBM in future updates will add more features.

What features will be available in future releases?
As we all know, BBM for Android and iOS coming in September, After a few weeks we expect a major update, introducing features in BlackBerry 10 platform, including:

•     Share Screen
•     Voice Calls
•     Video Calls

The application of BBM to iOS and Android also have the option of BBM Channels, in a similar way as in the case of BlackBerry 10.

Interaction of benzopyranone derivatives and related compounds with human concentrative nucleoside transporters 1, 2 and 3 heterologously expressed in porcine PK15 nucleoside transporter deficient cel

Biochem Pharmacol. 2009 Sep 4; Wang C, Pimple S, Buolamwini JKUnlike the major equilibrative nucleoside transporters, there is a dearth of potent specific inhibitors of concentrative nucleoside transporters (CNTs). We investigated the interaction of benzopyranone derivatives and related compounds with human (h) CNTs in newly established PK15NTD transfectant cells stably expressing hCNT1 or hCNT2, and previously established PK15NTD/hCNT3 cells. Flavones exhibited the highest inhibitory activity against hCNT2 and hCNT3, whereas the most potent selective inhibitor of hCNT1 was a coumarin derivative. hCNT3 was the only transporter that exhibited moderate sensitivity to the chalcones tested. The most active compound was 6-hydroxy-7-methoxyflavone, which was hCNT3-specific with an IC(50) of 0.57+/-0.20muM, and over 40-fold more potent than the standard CNT inhibitor, phloridzin (IC(50) of 25+/-3.5muM). The SAR (structure-activity relationship) shows that high potency against all three hCNTs is conferred by the presence of hydroxyl substituents at both the 7- and 8-positions of flavones and isoflavones. CoMFA (comparative molecular field analysis) and CoMSIA (comparative molecular similarity indices analysis) 3D-QSAR (three-dimensional quantitative structure-activity relationship) modeling indicated that electrostatic and hydrophobic properties were the most influential for interactions between the flavonoids and hCNT1, while electrostatic, hydrophobic and hydrogen bond donor properties were predominate for interactions with hCNT2 and hCNT3. The 3D-QSAR results also suggested possible commonalities in hydrogen bonding interactions of flavonoids and nucleosides, suggesting similarities between the hCNT-binding sites of the two classes of compounds. We report the most potent and selective non-nucleoside CNT inhibitors to date; which may serve as research tools and/or leads for further inhibitor development.

Is the test of senior friendly/child resistant packaging ethical?

Health Expect. 2009 Jul 24; Bix L, de la Fuente J, Pimple KD, Kou EResearch has documented the drastic reduction of unintentional poisonings of children since the introduction of child resistant (CR) packaging. However, studies also indicate that consumers report difficulty using CR packages, in part because tests which determine the 'senior friendliness' of CR designs that are used throughout the world disallow people with 'overt or obvious' disabilities from being test subjects. Our review of drug package usability suggests that the current tests of CR packaging can and should be revised to correct this problem. We use US legislation, regulation and data to exemplify these points, but the conclusions are applicable to all protocols that include the exclusionary provision.

Palliative Care for Children: Preparing Undergraduate Nursing Students.

Nurse Educ. 2009 July/August; 34(4): 162-165Schreiner LS, Pimple C, Wolf Bordonaro GPChildren with life-threatening illnesses rarely benefit from palliative services. Because nurses spend more time with dying children than any other healthcare professional does, it is essential that they are prepared to address the complicated physical, psychological, legal, ethical, and spiritual issues associated with terminal illness and death. The authors discuss a course that provides students with the knowledge, skills, and attitude needed to provide comprehensive care for pediatric patients and their families.