[Effectiveness of intravenous chemotherapy in the complex treatment of pulmonary tuberculosis]

Probl Tuberk. 1973; 51(10): 85-6Zits VR

[Determination of the blood thiol disulfide balance using the coulometric titration method]

Lab Delo. 1991; 33-5Zits SV

The cow with zits.

Curr Surg. 2001 Jan; 58(1): 1Pories WJ

Zits for health.

J Fam Pract. 1994 Feb; 38(2): 196Richards JW

[Coulometric method of determining sulfhydryl groups in the blood]

Lab Delo. 1988; 71-2Zits SV, Sopil'niak DS, Abaev AM

[Thiol compounds and erythrocyte membrane permeability in arterial hypertension]

Klin Med (Mosk). 1988 Oct; 66(10): 55-7Shulutko BI, SokolovskiÄ­ VV, Zits SV

[Recurrence of tuberculosis of the respiratory organs]

Probl Tuberk. 1984 Dec; 64-5Farnieva MA, Zits VR, Biazrov SKh, Shamileva FKh, Alikova RG

Pimple positives.

Cutis. 2005 Aug; 76(2): 96Weinberg JM

Simply a pimple, or is it worse?

JAAPA. 2007 Nov; 20(11): 15Monroe JR

Outcome of tibial plateau fractures managed with calcium phosphate cement Re: letter to the editor about an article in Injury 35 (2004) 913-918.

Injury. 2005 Aug; 36(8): 985; author reply 986Pimple MK

Ethics at the interface: A successful online seminar--commentary on "Reflections on teaching health care ethics on the web".

Sci Eng Ethics. 2005 Jul; 11(3): 495-9Pimple KD

Bridge plate osteosynthesis of humeral shaft fractures.

Injury. 2005 Apr; 36(4): 576Gibbs JR, Pimple M, Ricketts D

Anatomical considerations for percutaneous proximal humeral fracture fixation [Injury 2004;35:1133-6].

Injury. 2005 Aug; 36(8): 986; author reply 987Pimple MK, Gaskin JS

Anchor failure following shoulder stabilisation: delayed diagnosis and potential consequences.

J R Army Med Corps. 2008 Sep; 154(3): 160-2Pimple MK, Clasper J

How accurate and reliable are doctors in estimating fracture angulation?

Injury. 2007 Feb; 38(2): 160-2Gaskin JS, Pimple MK, Wharton R, Fernandez C, Gaskin D, Ricketts DMThis study assessed the accuracy of doctors in estimating fracture angulation. Radiographs of fractured wrist and forearm of varying angulations were shown to all grades of doctors in the speciality of trauma and orthopaedics. They were asked to estimate the angulation at the fracture site without using a goniometer. The estimates were analysed for accuracy and variability. This study showed that doctors have a mean error of 8-9 degrees and had poor agreement with themselves and others. We recommend the use of a goniometer to assess fracture angulation.

Research misconduct and crime lessons from criminal science on preventing misconduct and promoting integrity.

Account Res. 2005 Jul-Sep; 12(3): 225-40Adams D, Pimple KDFor 200 years, criminologists theorized that delinquent and criminal acts arise from deviant psychological states (such as irrationality or immorality) and/or social conditions that produce these psychological states. This theoretical perspective, which is being duplicated in most efforts to understand and control research misconduct, has not been productive. More recently, criminological perspectives have emerged, emphasizing situational factors that enhance or restrict the opportunity for illegal or imprudent behavior. These so-called "opportunity" theories have been shown to have practical value in reducing crime rates. We explore the promise of these newer theories for the responsible conduct of research (RCR).

Nursing management of hearing impairment in nursing facility residents.

J Gerontol Nurs. 2008 Nov; 34(11): 9-17Adams-Wendling L, Pimple C, Adams S, Titler MGThis article has described the key points in the evidence-based practice guideline entitled Nursing Management of Hearing Impairment in Nursing Facility Residents. The guideline outlining the nursing management of nursing facility residents with hearing impairment is supported by 175 articles: 94 research articles (both experimental and descriptive) and 81 nonresearch articles (expert opinion). The full guideline includes the significance of hearing impairment, key definitions, individuals at risk, assessment criteria and tools, description of practice, and steps for evaluation and outcomes. We believe the implementation of this evidence-based practice guideline will improve the quality of life and quality of care of nursing facility residents.

Budgeting nursing workload for required minimum data set assessments.

J Nurs Manag. 2007 May; 15(4): 442-8Adams-Wendling L, DeDonder J, Tidwell S, Pimple C, Schmiot L, Okeson DAIM: The purpose of this study was to evaluate the reliability and validity of an instrument used to measure nursing workload of federally mandated assessments. Specifically, the instrument measures the nursing workload of the resident assessment instrument the mandated assessment tool used in nursing facilities. BACKGROUND: It is imperative that nursing managers and nurse executives in health care organizations have a process to budget Registered Nurse full-time equivalents required for federally mandated assessments. METHODS: The sample (N=48) included nursing facility minimum data set Coordinators. Reliability and validity scores of the nursing workload instrument are calculated using Pearson correlation coefficients (r). RESULTS: The nursing workload instrument demonstrated reliability and validity. Total nursing workload to complete the minimum data set for nursing facilities is summarized. CONCLUSION: The results provide support for a reliable and valid instrument to measure nursing workload for standardized minimum data set assessments.

A rose by any other name.

Skinmed. 2007 May-Jun; 6(3): 139-41Engle J, Desir J, Bernstein JMA 40-year-old man visited Haiti in the winter. His visit was uneventful, and he went swimming in the ocean. A week after his return he developed a small "pimple" on his right fifth finger. This condition progressed for several weeks, with new lesions developing over the extensor surface of his forearm and in the antecubital fossa. He had tender axillary adenopathy. The patient started a new job when he returned from Haiti, working 4 days per week in a greenhouse. He denied any fever, chills, or night sweats. He was in good health without any underlying chronic health problems. Physical examination revealed a small eschar over the distal phalanx of the patient's right fifth finger (Figure 1). There were 2 erythematous nodules over the extensor surface of his right forearm (Figure 2) as well as over the antecubital fossa (Figure 3). A punch biopsy was performed and results showed suppurative granulomatous dermatitis. Sporothrix schenckii was grown from the specimen.

Old World eyelid cutaneous leishmaniasis: a case report.

Dermatol Online J. 2005; 11(3): 29Mencía-Gutiérrez E, Gutiérrez-Díaz E, Rodríguez-Peralto JL, Monsalve-Córdova JLeishmania is a protozoa that may infect the skin, mucous, and viscera. The geographical distribution of cutaneous leishmaniasis (CL) is mainly determined by the sandfly vectors. The Old World type is mainly attributed to Leishmania major and Leishmania tropica, and in South of Europe only to Leishmania infantum. A 63-year-old woman, who noted a pimple on the external third of the left upper eyelid 6 months before. The lesion was nodular, well-defined and measured 1.1 cm in diameter and in height, simulating a basal cell carcinoma. It was surgically excised. CL diagnosis was made upon the histologic examination, which showed histiocytes with intracellular leishmania organisms. At 2 years followup, no evidence exists of cutaneous, mucous, or visceral involvement. Apart from carcinomas, nodular lesions with central ulceration are rare on the eyelid. A single cutaneous lesion of leishmania (oriental sore) has to be considered in the differential diagnosis, along with malignant eyelid neoplasms.

Effect of disjoining pressure on the drainage and relaxation dynamics of liquid films with mobile interfaces.

J Colloid Interface Sci. 2009 Apr 8; Tabakova SS, Danov KDThis work presents a generalized lubrication approximation of the drainage and relaxation of thin liquid films with tangentially mobile surfaces. The proposed model accounts for the dynamic effects and the role of surface forces of intermolecular origin. The van der Waals and hydrophobic attractive and the electrostatic and steric repulsive components of the disjoining pressure are included in the numerical calculations of the dynamics and relaxation of one-dimensional films. Different regimes of film drainage are discussed: regular and unstable mechanisms of thinning depending on the magnitude of the Reynolds number; pimple formation in the presence of large enough attractive surface forces; and stabilizing effects of the disjoining pressure repulsive components. In the case of relaxation, it is proven that the disturbances in the film thickness: decrease exponentially to the equilibrium state without taking into account the role of the disjoining pressure; increase very fast to the point of film rupture in the presence of attractive surface forces; oscillate with exponentially decreasing amplitudes towards the state of stable equilibrium when the electrostatic and steric repulsive forces are significant.

Unsmooth cuticles of soil animals and theoretical analysis of their hydrophobicity and anti-soil-adhesion mechanism.

J Colloid Interface Sci. 2006 Mar 15; 295(2): 490-4Jia XSoil adhesion is a natural phenomenon, and it is harmful to terrain machines and tillage equipment that have soil as their work medium, such as automobiles, tractors, earth-moving machines, spades, hoes, and plows. Soil adhesion increases motion resistance and energy consumption, quickens damage to the soil-engaging components, and lowers work quality. The biomimetic research has provided a promising method to solve the soil adhesion problem. In this work, the cuticles of typical soil animals were observed by scanning electron microscopy (SEM) and their wettability and mechanism of antiadhesion were analyzed in theory. The results of experimental observation have shown that the cuticles of soil animals have different unsmooth appearances, such as pimple-shaped, pit-like, and undee structures. But for the cross sections of the unsmooth cuticles, their common character is undee. Theoretical analysis has indicated that the larger the ratio of the amplitude of the wave to the period of the wave, the stronger the hydrophobicity, the more easily the composite interface between the liquid and the unsmooth cuticles forms, and the function of reducing soil adhesion of the unsmooth cuticles will be better.

Microvilli appear to represent the first step in actin bundle formation in Drosophila bristles.

J Cell Sci. 2004 Jul 15; 117(Pt 16): 3531-8Tilney LG, Connelly PS, Guild GMDuring bristle development the emerging bristle shaft, socket cell, and the apical surface of thoracic epithelial cells form tiny protuberances or pimples that contain electron-dense material located on the cytoplasmic surface of the pimple tip. In a few cases short actin filaments extend from this material into the cortical cytoplasm. When cultured in the presence of jasplakinolide, an agent that prevents filament disassembly, pimples elongate to form microvilli containing a core of crosslinked filaments. Emerging-bristle mutants delay cortical bundle formation and are aggregated by forked protein crossbridges. Using these mutants and enhancing core bundle formation with jasplakinolide we found that microvillar formation represents the first stage in the morphogenesis of much larger actin bundles in Drosophila bristle shaft cells. Evidence is presented showing that socket cells do not contain forked protein crossbridges, a fact that may explain why cortical bundles only appear in bristle shaft cells. Furthermore, as pimples and microvilli form in the absence of both forked and fascin crossbridges, we also conclude that neither of these crossbridges account for core bundle formation in microvilli, but there must exist a third, as yet unidentified crossbridge in this system. Immunocytochemisty suggested that this new crossbridge is not Drosophila villin. Finally, ultrastructural comparisons suggest that microspikes and microvilli form very differently.

Removal of copper from aqueous solution using newspaper pulp as an adsorbent.

J Hazard Mater. 2008 Nov 30; 159(2-3): 396-403Chakravarty S, Pimple S, Chaturvedi HT, Singh S, Gupta KKNewspaper pulp was found to be a potential adsorbent for removal of copper from aqueous medium. Detail adsorption study of Cu on newspaper pulp was investigated. Batch adsorption study was carried out as a function of contact time, adsorbent dose, temperature (303-323 K). The experimental data was analyzed using Freundlich, Langmuir, Dubinin-Radushkevich (D-R) and Redlich-Peterson (R-P) isotherm models. It was found that Freundlich, Langmuir and R-P models fitted well. pH variation study revealed that the adsorption increased with increase in pH of the solution. Maximum loading capacity was found to be 30 mg g(-1) at 20 mg L(-1) of initial Cu concentration. Adsorption data were analyzed using two kinetic models, Lagergren first order and pseudo second order. It was observed that pseudo second order represented the best correlation. Langmuir isotherm was used to obtain the thermodynamic parameters such as free energy (DeltaG degrees ), enthalpy (DeltaH degrees ) and entropy (DeltaS degrees ) of adsorption. The negative value of free energy and positive value of enthalpy change indicate that the adsorption of Cu on newspaper pulp is a spontaneous process and endothermic. The results of activation energy also confirmed that the adsorption of Cu on newspaper pulp is physical in nature. Present investigation emphasized that newspaper pulp may be utilized as a low cost adsorbent for copper removal.

Management of shoulder instability in a military population.

J R Army Med Corps. 2008 Mar; 154(1): 38-40Pimple MK, DaCosta A, Clasper JCOBJECTIVES: Recurrent instability is common after shoulder dislocation in the young, particularly those engaged in physical jobs or sport. The management of recurrent traumatic shoulder instability is predominantly operative. However, the best method of surgery i.e. open or arthroscopic is still a matter of debate. We have developed an algorithm to decide on the choice of surgery and the aim of this study is to report this and compare the two different groups of military patients. METHODS: A retrospective review of all shoulder stabilisations performed on military personnel, by a single surgeon, between August 2004 and August 2005 at a district general hospital serving both military and civilian population was undertaken. The presentation, clinical and operative findings were noted and compared in the groups treated by arthroscopic or open stabilisation. RESULTS: Using our protocol 39 shoulder stabilisations were performed in military personnel. Of the shoulders, 25 (64%) underwent arthroscopic and 14 (36%) underwent open stabilisation. The indication for surgery was more than 2 episodes of shoulder dislocation. Open surgery was found to be more common in those who had their first dislocation at a younger age. Bilateral shoulder laxity was the most common indication to choose the open method. Both open and arthroscopic stabilisation gave good results in the high demand military population. Only one patient had recurrent instability after arthroscopic procedure. However, this was not statistically significant when compared with open stabilisation.

Participation in biomedical research is an imperfect moral duty: a response to John Harris.

J Med Ethics. 2007 Jul; 33(7): 414-7Shapshay S, Pimple KDIn his paper "Scientific research is a moral duty", John Harris argues that individuals have a moral duty to participate in biomedical research by volunteering as research subjects. He supports his claim with reference to what he calls the principle of beneficence as embodied in the "rule of rescue" (the moral obligation to prevent serious harm), and the principle of fairness embodied in the prohibition on "free riding" (we are obliged to share the sacrifices that make possible social practices from which we benefit). His view that biomedical research is an important social good is agreed upon, but it is argued that Harris succeeds only in showing that such participation and support is a moral good, among many other moral goods, while failing to show that there is a moral duty to participate in biomedical research in particular. The flaws in Harris's arguments are detailed here, and it is shown that the principles of beneficence and fairness yield only a weaker discretionary or imperfect obligation to help others in need and to reciprocate for sacrifices that others have made for the public good. This obligation is discretionary in the sense that the individuals are free to choose when, where, and how to help others in need and reciprocate for earlier sacrifices. That Harris has not succeeded in claiming a special status for biomedical research among all other social goods is shown here.